Genome engineering: writing a better genome
نویسندگان
چکیده
منابع مشابه
Genome engineering: writing a better genome.
At first glance, the undergraduate biology curriculum at the Johns Hopkins University doesn't look all that different from other biology programs. All the usual suspects are on the schedule: General Biology and Cell Biology, Virology and Genetics, Immunology and Biochemistry. But down at the bottom of that list is something that you don't see every day — Biology 420: Build-a-Genome. While the c...
متن کاملDirected genome engineering for genome optimization.
The ability to develop nucleases with tailor-made activities for targeted DNA double-strand break induction at will at any desired position in the genome has been a major breakthrough to make targeted genome optimization feasible in plants. The development of site specific nucleases for precise genome modification has expanded the repertoire of tools for the development and optimization of trai...
متن کاملPrecision genome engineering
More broadly, however, we need to get the message to the ordinary taxpayer and to legislators of the importance of basic research and of stable, longterm funding for research that only governments can afford to support. I wonder if we could convince Fox News in the USA to have a ‘redneck scientist’ segment in which a ‘salt of the earth’ scientist explains to the Fox audience how basic research ...
متن کاملPredicting CpG Islands and DNA Methlation in the Cow Genome Using DNA Microarray Meta-Analysis and Genome Wide Scanning
DNA methylation is a type of epigenetic changes that directly affects DNA. In mammals, DNA methylation is essential for fetal development and stem cell differentiation and this phenomenon essentially occurs within the CpG islands. In this study, two methods were used to study the DNA methylation profile of cow genome. In the first method, the DNA methylation profile of the differentially expres...
متن کاملA CRISPR method for genome engineering
Clustered regularly interspaced short palindromic repeat (CRISPR) RNA-guided adaptive immune systems that protect bacteria and archaea from infection by viruses are now being routinely repurposed for genome engineering in a wide variety of cell types and multicellular organisms.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BioTechniques
سال: 2012
ISSN: 0736-6205,1940-9818
DOI: 10.2144/000113934